5. Spinraza
Spinraza, also known as nusinersen, replaces a protein called survival motor neuron or SMN. This particular protein is critical in the survival and function of motor neurons.
Patients with SMA are missing a part of a gene that is responsible for the production of SMN protein. Spinraza is a synthetic type of gene that can replace the missing protein. It relieves symptoms of SMA.
4. Zolgensma
Zolgesma is a gene therapy that can help treat SMA. It enhances SMN by delivering a healthier version of the gene. It replaces the missing part of the gene so that it could function well to produce the SMN protein
Zolgensma is delivered through injection and is a one-time treatment. This particular type of treatment is best delivered soon after the diagnosis of SMA.
3. Postural Drainage
Postural Drainage makes use of gravity to mobilize mucus out of the lungs. It requires the patient to be in certain positions so that gravity can help loosen and drain mucus in the lungs. Hence, mucus can then be expelled through coughing.
Sitting down is an example of a position used for postural drainage. Another position for this particular type of treatment requires the patient to lie on the side, back, or stomach.
2. Intrapulmonary Percussive Ventilation (IPV)
Intrapulmonary Percussive Ventilation (IPV) is a type of ventilation that makes use of short, sharp bursts of air to open up the airways. The rapid bursts of air can help loosen and remove mucus from the walls of the airways. This is a beneficial side effect.
IPV) helps mucus become less sticky. Considering the high flow rate of this particular device, the patient must take deep breaths to help move the air around.
1. High-Frequency Chest-Wall Oscillation (HFCWO)
High-Frequency Chest-Wall Oscillation, also known as HFCWO, is another SMA treatment that helps clear the airway. This particular treatment requires a wearable device in the form of a vest.
The vest vibrates so that it can loosen and mobilize mucus to the upper airways. The patient can cough out the mucus for removal. Suction can also be used to remove mucus.
These are just some of the spinal muscular atrophy treatments worth knowing about.